Dear Dr. Mombelli,
The driving force for developing of AW for Ecotox endpoint is to provide to the user a tool for automated prediction of aquatic toxicity (LC50, 96h, mortality, fish) which also to follow the tox regulation in Europe. The analysis performed before building the workflow showed that the most of data for fish was obtained using tests with the species P.promelas. Therefore, itt was chosen for the AW. However, the profilers used for grouping/subcategorization are not optimized specifically to this test organism species.
For more details on the selection of test organism species, profilers and criteria for subcategorization, you can see our recent publication focused on the automated and standardized workflows in Toolbox: Yordanova D., 2019 (https://www.sciencedirect.com/science/article/pii/S2468111318301269?via%3Dihub).
Dear Darina, Thank you very much for your answer!